sk mel 2 (ATCC)

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ATCC sk mel 2
Sk Mel 2, supplied by ATCC, used in various techniques. Bioz Stars score: 97/100, based on 777 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/sk+mel+2/SK-MEL-2/pm42883943-178-9-10
Average 97 stars, based on 777 article reviews

sk mel 2 - by Bioz Stars, 2026-11

97/100 stars

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Cell Culture:

Article Title: Melanoma resists chemotherapy through an adaptive mitochondrial response.
Article Snippet: .. Cell lines and cell culture Human melanoma cell lines, A375, SK-MEL-28, MeWo, Hs 852.T, SK-MEL-2, and 1205Lu, were obtained from the American Type Culture Collection (ATCC), WM164 and 451Lu were sourced from Rockland, Inc. .. The murine melanoma cell lines YUMM1.7 and B16-F10 were also acquired from ATCC.

Recombinant:

Article Title: Untranslated region rewiring defines a novel class of oncogene fusions.
Article Snippet: REAGENT or RESOURCE SOURCE IDENTIFIER Antibodies P-MET-Y1234/1235 Cell Signaling Technology Cat# 3077; RRID: AB_2143886 Total MET Cell Signaling Technology Cat# 3148; RRID: AB_2143834 Total MET R&D Systems Cat# AF276; RRID: AB_355289 MET-PE R&D Systems Cat# FAB3582P; RRID: AB_357005 gamma-H2AX-S139 Cell Signaling Technology Cat# 9718; RRID: AB_2118009 H3-HRP Abcam Cat# ab21054; RRID: AB_446995 Actin-HRP Abcam Cat# ab207674; RRID: AB_2868347 P-AKT-S473 Cell Signaling Technology Cat# 9271; RRID: AB_329825 Total AKT Cell Signaling Technology Cat# 9272; RRID: AB_329827 ERK1/2-P-T202/Y204 Cell Signaling Technology Cat# 9101; RRID: AB_331646 Total ERK1/2 Cell Signaling Technology Cat# 9102; RRID: AB_330744 c-Myc Abcam Cat# ab32072; RRID: AB_731658 E-Cadherin Abcam Cat# ab40772; RRID: AB_731504 ACTA2 Sigma-Aldrich Cat# A2547; RRID: AB_476701 ETV1 Abcam Cat# ab314874 FGFR1 Cell Signaling Technology Cat# 9740; RRID: AB_11178516 P-FGFR1-Y653/654 Cell Signaling Technology Cat# 52928; RRID: AB_2799398 FRS2-P-Y436 Cell Signaling Technology Cat# 3861; RRID: AB_2092546 Anti-rabbit IgG-HRP Cell Signaling Technology Cat# 7074; RRID: AB_2099233 Anti-mouse IgG-HRP Cell Signaling Technology Cat# 7076; RRID: AB_330924 Anti-goat IgG-AlexaFluor 488 Thermo Fisher Scientific Cat# A11055; RRID: AB_2534102 Anti-rabbit IgG-AlexaFluor 647 Thermo Fisher Scientific Cat# A21245; RRID: AB_2535813 Anti-mouse IgG-AlexaFluor 555 Thermo Fisher Scientific Cat# A21422; RRID: AB_2535844 Chemicals, peptides, and recombinant proteins Recombinant human HGF R&D Systems Cat# 294-HGN/CF (Continued on next page) 16 Cell Reports 45, 118145, October 27, 2026 .. REAGENT or RESOURCE SOURCE IDENTIFIER Recombinant human FGF2 R&D Systems Cat# 3718-FB Cycloheximide Sigma-Aldrich Cat# 18079 Blasticidin InvivoGen Cat# ant-bl-05 Tepotinib Selleckchem Cat# S7067 AZD4547 Selleckchem Cat# S2801 TRIzol Reagent Thermo Fisher Scientific Cat# 15596026 Critical commercial assays Nano-Glo Dual-Luciferase Reporter Assay System Promega Cat# N1610 CyQUANT Cell Proliferation Assay Kit Thermo Fisher Cat# C35011 Maxwell RSC Blood DNA Kit Promega Cat# AS1400 Maxwell RSC miRNA Kit Promega Cat# AS1460 Zero Blunt TOPO PCR Cloning Kit Thermo Fisher Cat# 450031 Deposited data AACR Project GENIE v17 AACR https://www.aacr.org/professionals/research/ aacr-project-genie/ TCGA fusion dataset NCI GDC https://portal.gdc.cancer.gov Raw data and analysis scripts This study https://doi.org/10.5281/zenodo.21804107 Experimental models: Cell lines EKVX (H. sapiens) NCI RRID: CVCL_1195 HT-29 (H. sapiens) ATCC RRID: CVCL_0320 SW948 (H. sapiens) ATCC RRID: CVCL_0632 CAPAN-1 (H. sapiens) ATCC RRID: CVCL_0237 786-O (H. sapiens) ATCC RRID: CVCL_1051 COLO-679 (H. sapiens) DSMZ RRID: CVCL_1130 SK-MEL-2 (H. sapiens) ATCC RRID: CVCL_0069 A172 (H. sapiens) ATCC RRID: CVCL_0131 LN405 (H. sapiens) DSMZ RRID: CVCL_1379 JHUEM7 (H. sapiens) Creative Bioarray RRID: CVCL_4658 SW756 (H. sapiens) ATCC RRID: CVCL_1727 SNU245 (H. sapiens) Korean Cell Line Bank RRID: CVCL_5038 TOV112D (H. Sapiens) ATCC RRID: CVCL_3612 T47D (H. Sapiens) NCI RRID: CVCL_0553 U2OS (H. Sapiens) ATCC RRID: CVCL_0042 Oligonucleotides Primers for TaqMan assays, 5′RACE, and Sanger sequencing, see Table S13 This study N/A Recombinant DNA pNLuc-AK3-hPGK Addgene 242357 pNLuc-CAPZA2-hPGK Addgene 242358 pNLuc-ETV1-hPGK Addgene 242359 pNLuc-ETV4-hPGK Addgene 242360 pNLuc-FGFR1-hPGK Addgene 242362 pNLuc-FGFR2-hPGK Addgene 242363 pNLuc-HELZ-hPGK Addgene 242364 pNLuc-JAK2-hPGK Addgene 242365 pNLuc-KAT7-hPGK Addgene 242366 pNLuc-KCND3-hPGK Addgene 242367 pNLuc-Kozak-hPGK (no UTR control) Addgene 242368 (Continued on next page) Cell Reports 45, 118145, October 27, 2026 17 ..

Luciferase:

CyQUANT Assay:

Proliferation Assay:

Polymerase Chain Reaction:

Cloning:

Analysis:

DNA Sequencing:

Control:

Multiple Displacement Amplification:

Article Title: Redox cycling nitroxide limits cellular iron availability and selectively inhibits iron-sulfur cluster metabolism
Article Snippet: PPAT (15401-1-AP), LIAS (11577-1-AP) were from Proteintech. .. Cells: 5637, A-172, 786-O, A-253, A-375, A549, ACHN, AGS, AN3 CA, AsPC-1, BT-20, BT-549, BxPC-3, CAL 27, Calu-1, CAMA-1, DBTRG-05MG, Detroit 562, DoTc2 4510, DU 145, FaDu, HCC70, HCC827, HCT-15, HEC-1-A, HEC-1-B, Hep G2, Hs 578T, HT-1080, J82, LN-229, LNCaP, MDA-MB-231, MIA PaCa-2, NCI-H2052, NCI-H647, NCI-N87, PC-3, SH-SY5Y, SK-ES-1, SK-MEL-2, SK-OV-3, SNU-387, SNU-423, TT, U-2 OS, U-87 MG, UM-UC-3 from American Type Culture Collection; 647-V, BEN, CAL-33, EFM19, KYSE-30, OE-33, SK-MEL-30 from DSMZ, KP-2, OUMS-23 from JCRB, Chemicals: RPMI (MT10040CV) was from Corning; PrimeStar HS DNA Polymerase Premix (R040A) was from Takara; RNeasy Plus Mini Kit (74136), Qiaprep Spin Miniprep Kit (27106), and QIAquick Gel Extraction Kit (28706) were from Qiagen. .. 4-hydroxy-2,2,6,6-tetramethyl-1-piperidinyloxy (Tempol, 27051), Erastin (S7242) was from Selleckchem. (+)-Sodium L-ascorbate(A4034), 6-Hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid (Trolox, 238813), Pyridoxal isonicotinoyl hydrazine (PIH, 528110), deferoxamine mesylate (D9533), ferrostatin-1 (SML0583), iron(III) nitrate (F8508), Hydrogen Peroxide(216763) were from Sigma-Aldrich; KI696 (HY-101140) from MedChemExpress shRNAs were obtained from the The RNAi Consortium (TRC) or identical sequences cloned into pLKO.1p: shGFP, TRCN0000072186; shNFS1, TRCN0000229753.

Article Title: Redox cycling nitroxide limits cellular iron availability and selectively inhibits iron-sulfur cluster metabolism.
Article Snippet: PPAT (15401-1-AP), LIAS (11577-1-AP) were from Proteintech. .. Cells: 5637, A-172, 786-O, A-253, A-375, A549, ACHN, AGS, AN3 CA, AsPC-1, BT-20, BT-549, BxPC-3, CAL 27, Calu-1, CAMA-1, DBTRG-05MG, Detroit 562, DoTc2 4510, DU 145, FaDu, HCC70, HCC827, HCT-15, HEC-1-A, HEC-1-B, Hep G2, Hs 578T, HT-1080, J82, LN-229, LNCaP, MDA-MB-231, MIA PaCa-2, NCI-H2052, NCI-H647, NCI-N87, PC-3, SH-SY5Y, SK-ES-1, SK-MEL-2, SK-OV-3, SNU-387, SNU-423, TT, U-2 OS, U-87 MG, UM-UC-3 from American Type Culture Collection; 647-V, BEN, CAL-33, EFM19, KYSE-30, OE-33, SK-MEL-30 from DSMZ, KP-2, OUMS-23 from JCRB, Chemicals: RPMI (MT10040CV) was from Corning; PrimeStar HS DNA Polymerase Premix (R040A) was from Takara; RNeasy Plus Mini Kit (74136), Qiaprep Spin Miniprep Kit (27106), and QIAquick Gel Extraction Kit (28706) were from Qiagen. .. 4-hydroxy-2,2,6,6tetramethyl-1-piperidinyloxy (Tempol, 27051), Erastin (S7242) was from Selleckchem. (+)-Sodium L-ascorbate(A4034), 6-Hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid (Trolox, 238813), Pyridoxal isonicotinoyl hydrazine (PIH, 528110), deferoxamine mesylate (D9533), ferrostatin-1 (SML0583), iron(III) nitrate (F8508), Hydrogen Peroxide(216763) were from Sigma-Aldrich; KI696 (HY-101140) from MedChemExpress shRNAs were obtained from the The RNAi Consortium (TRC) or identical sequences cloned into pLKO.1p: shGFP, TRCN0000072186; shNFS1, TRCN0000229753.

Gel Extraction:

other:

Article Title: Translational Suppression of KRAS and NRAS via RNA G-Quadruplex-Targeting Small Molecules for Colorectal Cancer Therapy.
Article Snippet: RAS mutations are major drivers of tumorigenesis and represent important therapeutic targets; however, most remain resistant to effective pharmacological inhibition.. KRAS and NRAS mRNAs contain guanine (G)-rich regions, forming stable Gquadruplexes (G4s) that regulate translation.. Targeting and stabilizing these G4 structures with specific ligands may suppress their expression, offering a potential therapeutic strategy for RASdriven cancers.

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